Results 61 to 70 of about 13,306 (96)

Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory‐Denk body formation

The FASEB Journal, 2012
Raymond Kwan, S. Hanada, M. Harada, P. Strnad, Daniel H. Li, M. Omary   +5 more
semanticscholar   +1 more source

Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells.

Experimental and molecular pathology (Print), 2012
B. French, J. Oliva, F. Bardag-Gorce, J. Li, J. Zhong, V. Buslon, S. French   +6 more
semanticscholar   +1 more source

Gender dimorphic formation of Mallory‐Denk bodies and the role of xenobiotic metabolism and oxidative stress

Gastroenterology, 2010
Natasha T. Snider, S. Hanada, E. Brunt, P. Hollenberg, M. Omary   +4 more
semanticscholar   +1 more source

A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation

Molecular and Cellular Proteomics, 2020
Mallory-Denk-bodies (MDBs) are hepatic inflammation-associated protein aggregates. Similar protein aggregation in neurodegenerative diseases also triggers inflammation and NF-κB-activation by an as yet uncharacterized non-canonical mechanism.
Michael J Trnka, Do-Hyung Kim, Maria Almira Correia   +2 more
exaly   +2 more sources

The role of Tec kinase signaling pathways in the development of Mallory Denk Bodies in balloon cells in alcoholic hepatitis

Experimental and Molecular Pathology, 2017
N. Afifiyan, B. Tillman, B. French, O. Sweeny, M. Masouminia, S. Samadzadeh, S. French   +6 more
exaly   +2 more sources

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„Mama denk’ an mich“ (MAMADAM) – ein multimodales Therapieprogramm für suchtkranke Schwangere, Mütter und Väter im Rahmen der psychiatrischen Institutsambulanz

Sucht : Zeitschrift für Wissenschaft und Praxis, 2018
Zusammenfassung. Zielsetzung: Suchtkranke Personen und insbesondere Methamphetamin (MA) -abhängige schwangere Frauen, Mütter und Väter brauchen spezifische Hilfsangebote für sich und ihre Kinder.
C. Groß, S. Hahn, M. Spreer, S. Behrendt, J. Dinger, J. Reichert, M. Pilhatsch, U. Zimmermann   +7 more
semanticscholar   +1 more source

Cross β-Sheet Conformation of Keratin 8 Is a Specific Feature of Mallory–Denk Bodies Compared With Other Hepatocyte Inclusions

Gastroenterology, 2011
Vineet Mahajan, Therese Klingstedt, K Peter R Nilsson   +2 more
exaly   +2 more sources

Ufmylation and FATylation pathways are downregulated in human alcoholic and nonalcoholic steatohepatitis, and mice fed DDC, where Mallory–Denk bodies (MDBs) form

Experimental and Molecular Pathology, 2014
H. Liu, J. Li, B. Tillman, B. French, S. French   +4 more
exaly   +2 more sources

IL-8 signaling is up-regulated in alcoholic hepatitis and DDC fed mice with Mallory Denk Bodies (MDBs) present

Experimental and Molecular Pathology, 2015
Hui Liu, B. French, T. Nelson, Jun Li, B. Tillman, S. French   +5 more
exaly   +2 more sources

The inflammasome in alcoholic hepatitis: Its relationship with Mallory–Denk body formation

Experimental and Molecular Pathology, 2014
Recent studies indicate that the inflammasome activation plays important roles in the pathogenesis of alcoholic hepatitis (AH). Nod-like receptor protein 3 (NLRP3) is a key component of the macromolecular complex that is so called the inflammasome that ...
Yue Peng, B. French, B. Tillman, T. Morgan, S. French   +4 more
exaly   +2 more sources