Results 181 to 190 of about 481,012 (228)

Can Foot Dermatophyte Infections Signal Future Diabetes Risk? Findings from a Register-based Study. [PDF]

open access: yesActa Derm Venereol
Frølunde AS   +5 more
europepmc   +1 more source

A Growth Chart for KBG Syndrome

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Karen J. Low   +6 more
wiley   +1 more source

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda   +9 more
wiley   +1 more source

Correction: A novel high-throughput qPCR chip for solving co-infections in RAS farmed rainbow trout. [PDF]

open access: yesSci Rep
Sørensen J   +6 more
europepmc   +1 more source

Acoustofluidic Patterning for Improved Microtissue Histology

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh   +13 more
wiley   +1 more source

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

Residue‐Specific Signatures of Structural Water Identified by Dissolution Dynamic Nuclear Polarization with UV‐Generated Radicals

open access: yesAngewandte Chemie, EarlyView.
Structural water molecules in proteins are notoriously hard to detect in solution. Hyperpolarized water with UV radicals as polarizing agents provides the sensitivity and resolution to detect residue‐specific signatures of structural water with NMR spectroscopy.
Fabian Hecker   +3 more
wiley   +1 more source

Positive Predictive Values of Familial Hypercholesterolemia Diagnoses in the Danish National Patient Registry and the Danish Familial Hypercholesterolemia Registry - A Validation Study. [PDF]

open access: yesClin Epidemiol
Knold J   +24 more
europepmc   +1 more source

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