Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch +9 more
wiley +1 more source
Experimental constraints on a long-lived magma layer at the Martian core-mantle boundary. [PDF]
Pierru R +9 more
europepmc +1 more source
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil +7 more
wiley +1 more source
Mechanical Investigation of CuZn30 Brass Under Conditions of Variable Axisymmetric Deformation. [PDF]
Weiler W, Jaśkiewicz K.
europepmc +1 more source
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source
Evidence of somatic cell reprogramming toward embryogenic competence revealed through morphoanatomical and biochemical transitions in Piper aduncum L. [PDF]
de Souza NB +2 more
europepmc +1 more source
dynoGP: Deep Gaussian Processes for Dynamic System Identification
This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli +3 more
wiley +1 more source
SonarReg-GS SLAM: Sparse Sonar-Guided Depth Regularization for Underwater Gaussian Splatting SLAM. [PDF]
Yang W, Qian X, Liu X, Leng J.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Tissue-stiffness-driven platelet activation emerges as a potential target for breast cancer prevention and treatment. [PDF]
Heenkenda MK +8 more
europepmc +1 more source

