Results 51 to 60 of about 86,412 (245)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Ai-Optimized 3D-Printed Abutments In Prosthodontics
International Dental JournalAim or purpose: To overcome the limitations of traditional abutments in biomechanical adaptation, this study integrates AI-driven biomechanical optimization and additive manufacturing to evaluate 3D-printed abutments' precision, stability, and ...
Lili Wang +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2007 In condensed matter physics, the study of electronic states with SU(N) symmetry has attracted considerable and growing attention in recent years, as systems with such a symmetry can often have a spontaneous symmetry-breaking effect giving rise to a novel
G. C. Guo +7 more
core +1 more source
Designing manufacturable viscoelastic devices using a topology optimization approach within a truly-mixed fem framework [PDF]
, 2016 A new approach to topology optimization is presented that is based on the minimization of the input/output transfer function H∞norm. Additionally, by properly selecting input and output vector, the approach is recognized to minimize an entirely new ...
Cinquini, Carlo +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Robust topology optimization of three-dimensional photonic-crystal band-gap structures [PDF]
, 2014 We perform full 3D topology optimization (in which "every voxel" of the unit cell is a degree of freedom) of photonic-crystal structures in order to find optimal omnidirectional band gaps for various symmetry groups, including fcc (including diamond ...
Freund, Robert M. +4 more
core +2 more sources
Advanced Engineering Materials, EarlyView.This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel +3 more
wiley +1 more source
Topology Optimized Multi-layered Meta-optics
, 2017 We propose a general topology optimization framework for metasurface inverse design that can automatically discover highly complex multi-layered meta-structures with increased functionalities.
Capasso, Federico +4 more
core +1 more source
Rapidity Gaps in DIS through Soft Colour Interactions [PDF]
, 1995 We present a new mechanism for the creation of large rapidity gaps in DIS events at HERA. Soft colour interactions between perturbatively produced partons and colour-charges in the proton remnant, modifies the colour structure for hadronization giving ...
Edin, A., Ingelman, G., Rathsman, J.
core +2 more sources