Results 101 to 110 of about 761,172 (262)

Big data clustering with varied density based on MapReduce

Journal of Big Data, 2019
The DBSCAN algorithm is a prevalent method of density-based clustering algorithms, the most important feature of which is the ability to detect arbitrary shapes and varied clusters and noise data. Nevertheless, this algorithm faces a number of challenges,
Safanaz Heidari, Mahmood Alborzi, Reza Radfar, Mohammad Ali Afsharkazemi, Ali Rajabzadeh Ghatari   +4 more
doaj   +1 more source

Spectral density-based clustering algorithms for complex networks. [PDF]

Front Neurosci, 2023
Ramos TC, Mourão-Miranda J, Fujita A.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Zanthoxylum infructescence detection based on adaptive density clustering

Journal of Agricultural Engineering
Infructescence detection during the early fruiting stage is a necessary preliminary work to estimate the yield of Zanthoxylum. The purpose of this research is to detect and quantify the infructescences on the images of early fruit-bearing branches of ...
Diwei Wu, Shaohua Zeng, Shuai Wang, Yanan Chen, Yidan Xu   +4 more
doaj   +1 more source

Fast Density Based Clustering Algorithm

International Journal of Machine Learning and Computing, 2013
Clustering problem is an unsupervised learning problem. It is a procedure that partition data objects into matching clusters. The data objects in the same cluster are quite similar to each other and dissimilar in the other clusters. The traditional algorithms do not meet the latest multiple requirements simultaneously for objects.
Priyanka Trikha, Singh Vijendra
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Model-based Methods of Classification: Using the mclust Software in Chemometrics [PDF]

Due to recent advances in methods and software for model-based clustering, and to the interpretability of the results, clustering procedures based on probability models are increasingly preferred over heuristic methods. The clustering process estimates a
Adrian Raftery, Chris Fraley
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source