Results 71 to 80 of about 761,172 (262)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The DBSCAN Clustering Algorithm on P Systems [PDF]
, 2019 We show how to implement the DBSCAN clustering algorithm (Density Based Spatial Clustering of Applications with Noise) on membrane systems using evolution rules with promoters and ...
Research Group on Natural Computing (Coordinador) +1 more
core
Scalable Density-Based Distributed Clustering [PDF]
, 2004 Clustering has become an increasingly important task in analysing huge amounts of data. Traditional applications require that all data has to be located at the site where it is scrutinized. Nowadays, large amounts of heterogeneous, complex data reside on different, independently working computers which are connected to each other via local or wide area
Januzaj, Eshref +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A novel bidirectional clustering algorithm based on local density
Scientific Reports, 2021 With the widely application of cluster analysis, the number of clusters is gradually increasing, as is the difficulty in selecting the judgment indicators of cluster numbers.
Baicheng Lyu, Wenhua Wu, Zhiqiang Hu
doaj +1 more source
Data clustering based on Langevin annealing with a self-consistent potential
, 2018 This paper introduces a novel data clustering algorithm based on Langevin dynamics, where the associated potential is constructed directly from the data.
Lafata, Kyle +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2018 Density-based spatial clustering of applications with noise (DBSCAN) is a data clustering algorithm which has the high-performance rate for dataset where clusters have the constant density of data points.
Arif, Rezoana Bente +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source