Results 81 to 90 of about 761,172 (262)

A density‐based enhancement to dominant sets clustering

open access: yesIET Computer Vision, 2013
Although there is no shortage of clustering algorithms, existing algorithms are often afflicted by problems of one kind or another. Dominant sets clustering is a graph‐theoretic approach to clustering and exhibits significant potential in various ...
Jian Hou   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Fast Clustering by Affinity Propagation Based on Density Peaks

open access: yesIEEE Access, 2020
Clustering is an important technique in data mining and knowledge discovery. Affinity propagation clustering (AP) and density peaks and distance-based clustering (DDC) are two significant clustering algorithms proposed in 2007 and 2014 respectively.
Yang Li, Chonghui Guo, Leilei Sun
doaj   +1 more source

Consistency, breakdown robustness, and algorithms for robust improper maximum likelihood clustering [PDF]

open access: yes, 2017
The robust improper maximum likelihood estimator (RIMLE) is a new method for robust multivariate clustering finding approximately Gaussian clusters.
Coretto, Pietro, Hennig, Christian
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Density-based clustering of polygons

open access: yes2009 IEEE Symposium on Computational Intelligence and Data Mining, 2009
Clustering is an important task in spatial data mining and spatial analysis. We propose a clustering algorithm P-DBSCAN to cluster polygons in space. P-DBSCAN is based on the well established density-based clustering algorithm DBSCAN. In order to cluster polygons, we incorporate their topological and spatial properties in the process of clustering by ...
Joshi, Deepti   +2 more
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Comprehensive analysis of clustering algorithms: exploring limitations and innovative solutions [PDF]

open access: yesPeerJ Computer Science
This survey rigorously explores contemporary clustering algorithms within the machine learning paradigm, focusing on five primary methodologies: centroid-based, hierarchical, density-based, distribution-based, and graph-based clustering. Through the lens
Aasim Ayaz Wani
doaj   +2 more sources

Clustering Algorithm Based on Density Peak and Neighbor Optimization

open access: yesJisuanji kexue yu tansuo, 2020
The time complexity of density peak algorithm in selecting the cluster center is very high. It needs to manually select the cutoff distance. When processing the manifold data, there may be multiple density peaks, which leads to the decrease of clustering
HE Yunbin, DONG Heng, WAN Jing, LI Song
doaj   +1 more source

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