Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Classical Density Functional Theory Coupled to the SAFT-VR Mie Equation of State: Extension to Associating Fluids. [PDF]
de Freitas Gonçalves A +2 more
europepmc +1 more source
Corrigendum: On the effective density dependence of vertex functionals in the relativistic hadron field theory [PDF]
Kristian Petrík, Štefan Gmuca
openalex +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Thermodynamically Consistent Enthalpies of Adsorption of Mixtures from Classical Density Functional Theory. [PDF]
Rehner P.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Multicomponent Double-Hybrid Density Functional Theory. [PDF]
Hasecke L, Mata RA.
europepmc +1 more source
Optical properties of the 11-cis retinal molecule from time-dependent density functional theory
Nkululeko Nokwara
openalex +1 more source
Density Functional Theory (B3LYP/6-31G*) Study of Toxicity of Polychlorinated Dibenzofurans [PDF]
Sabitu Babatunde Olasupo
openalex +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source

