Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Modeling Oxidative Stress-Linked Telogen Effluvium Using Monte Carlo Simulation of Published Trichoscopy Norms and Cannabis Exposure Distributions. [PDF]
CureusChadha A, Burmeister M, Poelker-Wells S.
europepmc +1 more source
Approximate particle number projection with density dependent forces: superdeformed bands in the A=150 and A=190 regions [PDF]
, 2000 A. Valor, J.L. Egido, L.M. Robledo
openalex +1 more source
Unified approach for molecular dynamics and density-functional theory.
Physical Review Letters, 1985 R. Car, M. Parrinello
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Exploring the interplay of electron density distribution and electrostatic potential in the interaction of nilutamide and flutamide with androgen receptors using quantum crystallography. [PDF]
RSC AdvBalasubramanian H +4 more
europepmc +1 more source
The Binding of Receptor-recognized α2-Macroglobulin to the Low Density Lipoprotein Receptor-related Protein and the α2M Signaling Receptor Is Decoupled by Oxidation [PDF]
, 1997 Sean M. Wu +2 more
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