Results 221 to 230 of about 7,360,473 (315)

An all‐electron numerical method for solving the local density functional for polyatomic molecules

, 1990
B. Delley
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Superenhancers shape the landscape and repair dynamics of transcription-associated DNA breaks in cancer. [PDF]

Sci Adv
Hidmi O, Shatleh D, Flayshman SO, Monin J, Aqeilan RI.   +4 more
europepmc   +1 more source

Interplay of carriers and deep-level recombination centers of 275-nm light-emitting diodes — Analysis on the parasitic peaks over wide ranges of temperature and injection density

, 2019
Tingzhu Wu, Yue Lin, Zhangbao Peng, Huashan Chen, Zhibin Shangguan, Meng Liu, Sung-Wen Huang Chen, Chih‐Hao Lin, Hao‐Chung Kuo, Zhong Chen   +9 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A molecular dynamics study of the structure and dynamics of screened polyelectrolyte complex materials.

Soft Matter
van Lange SGM, Vengallur N, Giuntoli A, van der Gucht J.   +3 more
europepmc   +1 more source

Deep learning-based segmentation and density estimation of corneal nerves and dendritic cells from In Vivo confocal microscopy images. [PDF]

Sci Rep
Ji M, Song Y, Roth J, Dashti A, Lazo J, Lincke A, Macedo AFT, Löwe W, Lagali N.   +8 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

A study on the refined population spatialization method integrating multi-source data: A case study of Yuxi city. [PDF]

PLoS One
Zhang F, Jiang F, Zhang Y, Xu J, Ye Y, Jia Z.   +5 more
europepmc   +1 more source

Development of novel aptamers for low-density lipoprotein particle quantification

, 2018
Daniel Klapak, Sarah Broadfoot, Gregory Penner, Anup K. Singh, Eshwar Inapuri   +4 more
openalex   +2 more sources