Results 41 to 50 of about 3,098,507 (269)

Density-Difference Estimation [PDF]

Neural Computation, 2013
We address the problem of estimating the difference between two probability densities. A naive approach is a two-step procedure of first estimating two densities separately and then computing their difference. However, this procedure does not necessarily work well because the first step is performed without regard to the second step, and thus a small ...
Sugiyama, Masashi, Kanamori, Takafumi, Suzuki, Taiji, Du Plessis, Marthinus Christoffel, Liu, Song, Takeuchi, Ichiro   +5 more
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Time-resolved X-ray imaging of the current filamentation instability in solid-density plasmas

Nature Communications
The streaming of energetic charged particles can magnetize astrophysical and laboratory plasmas via the current filamentation instability. Despite its importance, the experimental characterization of this instability has remained a challenge.
Christopher Schoenwaelder, Alexis Marret, Stefan Assenbaum, Chandra B. Curry, Eric Cunningham, Gilliss Dyer, Stefan Funk, Griffin D. Glenn, Sebastian Goede, Dimitri Khaghani, Martin Rehwald, Ulrich Schramm, Franziska Treffert, Milenko Vescovi, Karl Zeil, Siegfried H. Glenzer, Frederico Fiuza, Maxence Gauthier   +17 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Conserved densities [PDF]

Proceedings of the National Academy of Sciences, 1980
Conserved densities for Hamiltonian systems are shown to satisfy simple linear equations. These are essentially the original equations linearized around a particular solution. A number of examples are displayed, which pertain to many systems of physical interest.
openaire   +3 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Study on an Accurate Magnetic Network Model of Eccentric Magnet-Shaped Permanent Magnet Synchronous Motor

Applied Sciences
Permanent magnet synchronous motors (PMSMs) find extensive application across diverse domains thanks to their merits of high torque density and efficiency.
Tianle Li, Kai Yang, Fei Xiong, Cheng Luo, Zhihan Chen, Haiyang Hu, Tianxiang Liu   +6 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Tetramethylene Sulfone (TMS) as an Electrolyte Additive for High-Power Lithium-Ion Batteries

Batteries
High-power lithium-ion batteries impose stringent requirements on output power. Tetramethylene sulfone (TMS), serving as a novel electrolyte additive, effectively enhances the stability of electrolytes under high-voltage conditions due to its high flash ...
Wenting Liu, Gangxin Chen, Ningfeng Wang, Xianzhong Sun, Chen Li, Yanan Xu, Xiaohu Zhang, Xiong Zhang, Kai Wang   +8 more
doaj   +1 more source