Results 201 to 210 of about 3,935,284 (258)

Plant resistance and predators influence the density dependence of herbivore survival and distribution of herbivory. [PDF]

Ecol Evol
Paniagua Montoya M, Forde AJ, Inouye B, Underwood N.   +3 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Latitudinal patterns in stabilizing density dependence of forest communities. [PDF]

Nature
Hülsmann L, Chisholm RA, Comita L, Visser MD, de Souza Leite M, Aguilar S, Anderson-Teixeira KJ, Bourg NA, Brockelman WY, Bunyavejchewin S, Castaño N, Chang-Yang CH, Chuyong GB, Clay K, Davies SJ, Duque A, Ediriweera S, Ewango C, Gilbert GS, Holík J, Howe RW, Hubbell SP, Itoh A, Johnson DJ, Kenfack D, Král K, Larson AJ, Lutz JA, Makana JR, Malhi Y, McMahon SM, McShea WJ, Mohamad M, Nasardin M, Nathalang A, Norden N, Oliveira AA, Parmigiani R, Perez R, Phillips RP, Pongpattananurak N, Sun IF, Swanson ME, Tan S, Thomas D, Thompson J, Uriarte M, Wolf AT, Yao TL, Zimmerman JK, Zuleta D, Hartig F.   +51 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Long-term dynamics of density dependence reveals a more stable effect of the neighborhood on tree growth than tree survival. [PDF]

PLoS One
Wang L, Wu J, Chen F.
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Density dependence maintains long-term stability despite increased isolation and inbreeding in the Florida Scrub-Jay. [PDF]

Ecol Lett
Summers J, Cosgrove EJ, Bowman R, Fitzpatrick JW, Chen N.   +4 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Density-dependence tips the change of plant-plant interactions under environmental stress. [PDF]

Nat Commun, 2020
Zhang R, Tielbörger K.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source