Results 71 to 80 of about 3,935,284 (258)
The Marsh fritillary (Euphydryas aurinia) (Lepidoptera: Nymphalidae) has declined across Europe, including the Czech Republic. Current conservation strategies rely on prevention of habitat loss and degradation, and increase in habitat quality and ...
Kamil ZIMMERMANN +8 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Detection of delayed density dependence in an orchid population
1 Annual censuses of Orchis morio (green-winged orchid) flowering spikes have been taken over a 27-year period in a replicated factorial experiment on the effects of fertilizer application.
Gillman, M. P., Dodd, M.
core +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The strain-dependence of the critical current density in the high-field superconductor Nb(_3)Sn [PDF]
Measurements of the critical current density (J_c) of Nb(_3)Sn superconducting wires were performed as a function of magnetic field (B ≤ 23 T), temperature (4.2 K ≤ T ≤ 12 K), and axial strain (-1.6% ≤ ɛ ≤ 0.7%).
Taylor, David Matthew Joseph
core
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Density-dependence in the declining population of the monarch butterfly [PDF]
The Eastern monarch butterfly population has significantly declined over the last two decades creating growing concerns around its conservation status. Here, we showed that the overwintering population exhibited a negative density-dependence (i.e.
Myron P. Zalucki +5 more
core +1 more source
Metabolic rate is closely linked to body mass and is widely used to relate physiological processes to ecological and evolutionary patterns. In small aquatic organisms, measurements of oxygen consumption rate (Mo2) are often limited by instrument ...
Dong In Kim +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

