Results 141 to 150 of about 5,440,548 (293)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Calculation of Strain Energy Density Function Using Ogden Model and Mooney-Rivlin Model Based on Biaxial Elongation Experiments of Silicone Rubber. [PDF]

Polymers (Basel), 2023
Yamashita Y, Uematsu H, Tanoue S.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Applied Filtered Density Function

Journal of Applied Fluid Mechanics, 2013
An overview is presented of recent advances in the filtered density function (FDF) modeling and simulation of turbulent combustion. The review is focused on the developments that have facilitated the FDF to be broadly applied in large eddy simulation ...
S.Levent Yilmaz, N. Ansari, P.H Pisciuneri, M.B. Nik, C.C. Otis, P. Givi   +5 more
doaj  

Construction of root tip density function and root water uptake characteristics in alpine meadows. [PDF]

Front Plant Sci, 2022
Deng B, Weng B, Yan D, Xiao S, Fang H, Li M, Wang H.   +6 more
europepmc   +1 more source

A nonparametric estimate of a multivariate density function [PDF]

Problem solving - nonparametric estimate of probability density ...
Loftsgaarden, D. O., Quesenberry, C. P.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Smart thermally responsive perovskite materials: Thermo-chromic application and density function theory calculation. [PDF]

Heliyon, 2023
Jiang N, Chen S, Wang J, He C, Fang K, Yin H, Liu Y, Li Y, Yu D.   +8 more
europepmc   +1 more source

The unique determination of density from high-order potentials [PDF]

The existence of higher-order potentials is postulated, and that the density function can be determined from this set of potentials is demonstrated. Moreover, it is shown that there is a one-to-one correspondence between such potentials and the density ...
Johnson, G. G.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source