Results 41 to 50 of about 5,186,590 (262)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Southeast Asia 1:250,000 [cartographic material] /
Various eds. "Constructed and molded in ... from ... 1:250,000, Series 1501 ..."; Also shows aeronautical information.; Includes index to adjoining sheets and glossary.; Raised relief model map series of Southeast Asia (Thailand and Indochina) showing ...
United States. Army Map Service.
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Natural hazards map of the Circum-Pacific Region [cartographic material] : Pacific Basin sheet /
Map modified 1992.; Depths shown by isolines.; "This map is a contribution to the International Decade for Natural Disaster Reduction (IDNDR)."; Accompanied by: Explanatory notes for the Natural hazards map of the Circum-Pacific region Pacific Basin ...
Circum-Pacific Map Project.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A map detailing the sites of interest and importance in the Prospect, NC, and the Robeson County area of North Carolina.
Robeson County Green Map Project
core +1 more source
Sanborn map key for Austin in Travis County, Texas, showing the areas covered by numbered map sheets that contain more precise details related to risk assessment for fire ...
Sanborn Map Company
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Sulu Archipelago 1:50,000 [cartographic material] /
1st ed. (AMS 1). Topographic maps of the Sulu Archipelago, Philippines. Relief shown by soundings, spot heights, contours, and form lines where shown at approximately 100 foot intervals, heights and depths in feet.; Standard map series designation ...
United States. Army Map Service.
core

