Results 121 to 130 of about 317,422 (308)
Advanced Science, EarlyView.Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang +11 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Consequences of Tooth Loss on Oral Function and need for Replacement of Missing Teeth Among Patients Attending Muhimbili Dental Clinic [PDF]
, 2011 Tanzanian oral health services constitute mainly of tooth extractions. Consequently, individuals susceptible to dental caries and periodontal diseases will have a substantial number of missing teeth, which can affect oral function.
Quaker, Andrewleon S
core
Advanced Science, EarlyView.A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang +8 more
wiley +1 more source
Dental Attendance Among the Elderly in Benin-city, Edo state
Background: Despite the increase in the elderly population globally, it appears that several studies focused on dental clinic attendance by other age groups and with sparse data on the elderly.
babalola, olajumoke +3 more
core +1 more source
Dental age determination in South Australian children [PDF]
, 1999 Thesis (M.D.S.) -- University of Adelaide, Dental School ...
Stephen, Soni
core
Dental Age-Group Classification from Panoramic Radiographs Using Convolutional Neural Networks
DiagnosticsBackground/Objectives: Determining chronological age is important in several domains, including forensic identification, clinical decision-making, legal matters, and immigration procedures.
Essraa Gamal Mohamed +4 more
doaj +1 more source
Advanced Science, EarlyView.In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source
The professional interactions between speech language therapist and dentist
Exploration of MedicineAim: This study investigates the collaborative efforts between speech language therapists and dentists to address the challenges faced by patients with concurrent dental and speech issues.
Martina Costanzo +4 more
doaj +1 more source
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source