Results 211 to 220 of about 621,199 (307)

A Hereditary Pulmonary Alveolar Proteinosis Caused by a Novel Hemizygous Variation of the CSF2RA Gene Case Report and Literature Review

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 12, December 2025.
This paper describe a 3‐year‐old girl with Turner syndrome who presented with recurrent cough and dyspnea and was diagnosed with hereditary PAP. Genetic analysis revealed a novel hemizygous mutation in the CSF2RA gene (NM_000402.4:c.200_204del, p.Asn67SerfsTer8), which was confirmed as a de novo pathogenic variant and had not been reported previously ...
Qiang Chen   +6 more
wiley   +1 more source

[Occurrence of dental alveolus traumas at the university clinics of Kinshasa: second part, preliminary study of 93 cases].

open access: yesThe Pan African medical journal, 2018
Adelin Nzudjom, Foche   +8 more
openaire   +2 more sources

Expression of SARS‐CoV‐2 entry‐associated proteins in COPD airways: an immunohistochemical study

open access: yesThe Journal of Pathology, Volume 267, Issue 4, Page 424-434, December 2025.
Abstract Coronavirus disease 2019 (COVID‐19) is of special concern to patients with chronic obstructive pulmonary disease (COPD), given their susceptibility to exacerbations caused by respiratory tract infections. As the susceptibility of acquiring a SARS‐CoV‐2 infection in COPD remains unclear, this study explored the airway expression of SARS‐CoV‐2 ...
Larissa E Vlaming‐van Eijk   +5 more
wiley   +1 more source

A Unified Whole Lung PBK Model for Inhalational Uptake of Gases and Aerosols in Men

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 12, Page 2173-2185, December 2025.
ABSTRACT Assessing the risk or benefit of an inhaled substance is challenging due to the variety of forms it can take (gas, vapor, particle, or droplet) and the complex biological processes involved in its uptake and retention. Physiologically based kinetic (PBK) models offer an alternative to in vivo experiments.
Norman Nowak   +2 more
wiley   +1 more source

Advancing Tuberculosis Chemotherapy: Targeted Nanomedicines for the Mycobacterium TB Granuloma

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
This graphical abstract illustrates nanosystems used for targeted drug delivery into tuberculosis granulomas. It shows how targeting is influenced by size, pH, redox sensitivity, and surface charge. Various nanoparticles are incorporated with drugs to enhance penetration, stability, and release.
Shreya Ranjith Singh   +3 more
wiley   +1 more source

Reduced Mitochondrial Adenine Nucleotide Translocase 1 (ANT1) Correlates With Aging‐Associated Airway Remodeling

open access: yesAging Cell, Volume 24, Issue 12, December 2025.
Adenine nucleotide translocase 1 (ANT1), a mitochondrial ATP transporter, is decreased in the lung epithelium of aged adults and aged mice correlating to pathogenic airway changes. Loss of ANT1 correlates with increased cellular senescence and changes in COL8A1 in the airway epithelium of the lung.
Roshani Jha   +5 more
wiley   +1 more source

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