A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi +5 more
wiley +1 more source
Effectiveness of modified clear aligner designs in mesialization of permanent molars: a typodont model study. [PDF]
Al Ali SM, Ghoneima A.
europepmc +1 more source
This study proposes a robust, generalizable new approach for facial type diagnosis. Based on landmark detection and pose normalization, a 94.7% diagnostic accuracy is achieved by Combined Heatmap Regression and Coordinate Regression network. This research makes the AI‐generated preliminary diagnosis more interpretable and reducing the impact of ...
Qianyang Xie +12 more
wiley +1 more source
Retrospective Assessment of Palatal Biofilm and Mucosal Inflammation Under Orthodontic Appliances in Young Adults (2022-2025): A Single-Center Cohort with Microbiologic Sub-Sampling. [PDF]
Dragos B +6 more
europepmc +1 more source
This study introduces an AI‐guided strategy to design 3D‐printed PEEK implants functionalized with a tryptophan‐enriched alginate hydrogel (TRYALPEEK). The modification improves hydrophilicity, reduces surface roughness, enhances cytocompatibility, and optimizes stress distribution. The platform offers a promising route for personalized implant design,
Wafa Benaatou +8 more
wiley +1 more source
Integrating 3D Digital Technology Advancements in the Fabrication of Orthodontic Aligner Attachments: An In Vitro Study. [PDF]
Nagib R, Chircu A, Szuhanek C.
europepmc +1 more source
Maxillary molar distalization with invisalign in adult patients: a preliminary study using iTero-created digital models. [PDF]
Liu S, Fan Y, Gao L, Ding Y.
europepmc +1 more source
The alleviation of asthma by polydatin is dependent on the blockage of the toll‐like receptor 4 (TLR4)/P2X7R synergy in macrophages. The blockage of the TLR4/P2X7R synergy results in decreased release and secretion of interleukin‐1β (IL‐1β) and IL‐18. In epithelial cells, low IL‐1β and IL‐18 levels inhibit mitochondrial damage and apoptosis.
Guangxing Li +9 more
wiley +1 more source
Co-delivery of orthodontic treatment: Perceptions of supervising clinicians and orthodontic therapists. [PDF]
Shelswell JD +3 more
europepmc +1 more source
Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures
Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick +9 more
wiley +1 more source

