Results 221 to 230 of about 776,529 (356)

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Monitoring the prevalence and predictors of dental diseases in dogs

Bulgarian Journal of Veterinary Medicine
The increase in the share of dogs with dental pathology against the background of the appearance of new probable risk factors (in particular, the introduction of new diets in feeding), determine the rele-vance of regular monitoring of the spread and ...
D. D. Bilyi, U. I. Voloboieva
doaj   +1 more source

Ultra-high performance liquid chromatography high-resolution mass spectrometry for metabolomic analysis of dental calculus from Duke Alessandro Farnese and Maria D'Aviz. [PDF]

Sci Rep, 2023
Riboni N, Bianchi F, Mattarozzi M, Peracchia M, Meleti M, Careri M.   +5 more
europepmc   +1 more source

What the pig ate: A microbotanical study of pig dental calculus from 10th–3rd millennium BC northern Mesopotamia

, 2015
Sadie Weber, Max Price
openalex   +2 more sources

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Dental Calculus Formation Rate: The Role of Salivary Proteome and Metaproteome. [PDF]

J Clin Periodontol
Cai W, Dubreuil N, Abu Nada L, Zhou WBS, Basiri T, Hadad A, Charde P, Ducret M, Tamimi F.   +8 more
europepmc   +1 more source

More than what we eat: Investigating an alternative pathway for intact starch granules in dental calculus using Experimental Archaeology. [PDF]

Quat Int, 2023
Delaney S, Alexander M, Radini A.
europepmc   +1 more source

Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice

Advanced Science, EarlyView.
An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen, Ruiqing Hou, Zhinan Chen, Junli Lu, Si Chen, Shisheng Xiong, Jianfeng Feng, Trevor W. Robbins, Haitao Yan, Xiao Xiao   +9 more
wiley   +1 more source

Modifiable early life risk factors for dental calculus in dogs: a retrospective cross-sectional study in Finland. [PDF]

BMC Vet Res
Hemida MBM, Holm S, Eklundh M, Hielm-Björkman A.   +3 more
europepmc   +1 more source