Results 251 to 260 of about 776,529 (356)

Synchrotron radiation-based phase-contrast microtomography of human dental calculus allows nondestructive analysis of inclusions: implications for archeological samples. [PDF]

J Med Imaging (Bellingham), 2022
Power RC, Henry AG, Moosmann J, Beckmann F, Temming H, Roberts A, Le Cabec A.   +6 more
europepmc   +1 more source

Structural characterization and decontamination of dental calculus for ancient starch research

, 2018
María Soto, Jamie Inwood, Siobhàn Clarke, Alison Crowther, Danielle Covelli, Julien Favreau, Makarius Itambu, Steve Larter, Patrick Lee, Marina Lozano, Jason Maley, Aloyce Mwambwiga, Robert Patalano, Ramaswami Sammynaiken, Josep María Vergès, Zhu Jian-feng, Julio Mercader   +16 more
openalex   +2 more sources

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Microparticles from dental calculus disclose paleoenvironmental and palaeoecological records. [PDF]

Ecol Evol
D'Agostino A, Di Marco G, Rolfo MF, Alessandri L, Marvelli S, Braglia R, Congestri R, Berrilli F, Fuciarelli MF, Ferracci A, Canini A, Gismondi A.   +11 more
europepmc   +1 more source

Assessing the validity of a calcifying oral biofilm model as a suitable proxy for dental calculus

, 2023
Bartholdy BP, Velsko IM, Gur-Arieh S, Fagernäs Z, Warinner C, Henry AG.   +5 more
europepmc   +1 more source

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

Advanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan, Han Ma, Jespar Chen, Gaifeng Ma, Alok Jha, Sipin Tan, Yaxi Zhu, Meidong Liu, Ke Liu, Xianzhong Xiao, Monowar Aziz, Huan Chen, Ping Wang, Huali Zhang   +13 more
wiley   +1 more source

Palaeoproteomic investigation of an ancient human skeleton with abnormal deposition of dental calculus. [PDF]

Sci Rep
Uchida-Fukuhara Y, Shimamura S, Sawafuji R, Nishiuchi T, Yoneda M, Ishida H, Matsumura H, Tsutaya T.   +7 more
europepmc   +1 more source

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

Advanced Science, EarlyView.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan, Fang Yang, Linlin Hou, Yan Zhang, Xin Pang, Yuqi Du, Hongyi Yan, Huanzhou Zhu, Yue Cheng, Yue Wu, Pinpin Jiang, Mengnan Guo, Mengying Zhang, Jinjie Guo, Huihui Hao, Yong Jiang, Yi Li, Yanxia Gao   +17 more
wiley   +1 more source

Metagenomic and paleopathological analyses of a historic documented collection explore ancient dental calculus as a diagnostic tool. [PDF]

Sci Rep
Austin RM, Honap TP, Mann AE, Hübner A, DeGaglia CMS, Warinner C, Zuckerman MK, Hofman CA.   +7 more
europepmc   +1 more source