Results 261 to 270 of about 699,876 (364)

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo   +15 more
wiley   +1 more source

The child dental care reform in Israel - age-related patterns of uptake: 2011 to 2022. [PDF]

open access: yesIsr J Health Policy Res
Dekel D   +5 more
europepmc   +1 more source

Changes in Antibiotic Redemption Related to Hungarian Dental Care During COVID-19

open access: gold
Nándor Kalas   +6 more
openalex   +1 more source

Multiscale 3D Whole Joint Cellular and Molecular Mapping Reveals Disease‐Specific Neurovascular Plasticity Underlying the Structure‐Pain Relationship

open access: yesAdvanced Science, EarlyView.
This study presents MUSIC, a novel immunostaining and clearing method coupled with large‐field light sheet microscopy, enabling 3D high‐resolution cellular and molecular mapping of intact musculoskeletal joints across species and joint types. Using joint degenerative and injury models, disease‐specific neurovascular alterations are uncovered, revealing
Peng Chen   +18 more
wiley   +1 more source

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li   +14 more
wiley   +1 more source

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

open access: yesAdvanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee   +6 more
wiley   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

open access: yesAdvanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi   +14 more
wiley   +1 more source

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