Results 121 to 130 of about 2,915 (197)

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

open access: yesCell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li   +24 more
wiley   +1 more source

COVID‐19's Shadow: The Effect of COVID‐19 on Cytopathology Specimens Received at an Academic Laboratory in Central South Africa

open access: yesCytopathology, EarlyView.
Due to global COVID‐19‐related disruptions in healthcare delivery, cytopathology laboratories experienced a reduction in specimen volume that did not fully recover post‐COVID‐19. The findings of the study highlighted the importance of resilient diagnostic services during health crises.
Courtney T. A. Bonato   +2 more
wiley   +1 more source

Older Adults' Access to Pharmacological Treatment, a Human Right to Health: Scoping Review (2020-2025). [PDF]

open access: yesPharmacy (Basel)
Cardona D   +6 more
europepmc   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo   +4 more
wiley   +1 more source

Comfort and Usability of Digital Versus Conventional Custom‐Fit Mouthguards: A Randomized Clinical Trial

open access: yesDental Traumatology, EarlyView.
ABSTRACT Background/Objectives The use of mouthguards protects teeth and the supporting tissues against impacts. Digital impressions and 3D‐printed models can reduce manufacturing steps and minimize discomfort. This study evaluated the fit, comfort, and usability of custom‐made mouthguards, obtained by conventional and digital workflow, in amateur ...
Maryuri Macías Bautista   +8 more
wiley   +1 more source

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