Results 121 to 130 of about 50,099 (251)

"We try our best": a qualitative study of care staff's perspectives on oral health care for persons with disabilities. [PDF]

open access: yesBMC Oral Health
Phlypo I   +6 more
europepmc   +1 more source

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

open access: yesClinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw   +30 more
wiley   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

open access: yesCell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang   +6 more
wiley   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

Hospital admissions and school absences of primary school children with and without neurodisability

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To inform integrated support by education and health services by comparing hospitalization and school absence rates during primary school in children with and without neurodisability. Method In this linked administrative data cohort study, we followed 2 351 589 children born in England between 2003 and 2008 from enrolment in Reception ...
Laura Gimeno   +23 more
wiley   +1 more source

‘Back to Basics’: A Self‐Administered Survey of Undergraduate Dentists' Prevalence, Impact and Understanding of Lower Back Pain

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction The aim of this paper is to assess the prevalence, impact, and understanding of Lower Back Pain (LBP) amongst final year dental students to inform the development of a module in the dental curriculum. LBP has a significant impact on the dental workforce; yet little is reported about the profession's knowledge, or the necessity for
Samuel Cope   +3 more
wiley   +1 more source

Clinical and self‐reported measurements to be included in the core elements of the World Dental Federation's theoretical framework of oral health

open access: yesInternational Dental Journal, EarlyView., 2020
Introduction Oral health is part of general health, and oral diseases share risk factors with several non‐communicable diseases. The World Dental Federation (FDI) has published a theoretical framework illustrating the complex interactions between the core elements of oral health (CEOHs): driving determinants, moderating factors, and general health and ...
Hanna Ahonen   +5 more
wiley   +1 more source

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