Results 41 to 50 of about 29,108 (256)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dental diseases and factors defining utilization of dental care services among rural children aged 12 years in Nellore District, Andhra Pradesh: A community-based study

Journal of Pharmacy and Bioallied Sciences, 2021
Background: Rural children are predisposed to variety of dental problems, which may influence their overall health and well-being. Despite relentless efforts and achievements in oral health promotion by authorities, its impact seems limited in rural ...
Chandrasekhara Reddy Vuyyuru, Rajeshree Narayan Rangari, Gowri Sankar Singaraju, Nagarjuna Pottem   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Socioeconomic-Related Inequalities in Dental Care Utilization in Northwestern Iran

Clinical, Cosmetic and Investigational Dentistry, 2020
Satar Rezaei,1 Mohammad Habibullah Pulok,2 Telma Zahirian Moghadam,3 Hamed Zandian3 1Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Nova Scotia Health Authority ...
Rezaei S, Pulok MH, Zahirian Moghadam T, Zandian H   +3 more
doaj  

Evaluating components of dental care utilization among adults with diabetes and matched controls via hurdle models

BMC Oral Health, 2012
Background About one-third of adults with diabetes have severe oral complications. However, limited previous research has investigated dental care utilization associated with diabetes.
Chaudhari Monica, Hubbard Rebecca, Reid Robert J, Inge Ronald, Newton Katherine M, Spangler Leslie, Barlow William E   +6 more
doaj   +1 more source

Utilization of dental care service and associated factors among pre-school children in northwest China over the past decade

BMC Oral Health, 2023
Objective The purpose of this study was to analyze the factors influencing the utilization of oral health care among 5 years old children. Methods We conducted two observational cross-sectional studies.
Xiao Hu, Xiaoyu Fan, Jiangang Tian, Bin Zhang, Ruizhe Huang   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

How does legal status matter for oral health care among Mexican-origin children in California?

SSM: Population Health, 2017
This research examines the relationship between legal status and oral health care among Mexican-origin children. Using the 2001–2014 California Health Interview Surveys, the objectives are: (1) to demonstrate population-level changes in the legal ...
R.S. Oropesa, Nancy S. Landale, Marianne M. Hillemeier   +2 more
doaj   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source