Results 31 to 40 of about 8,561 (206)

Class-I and Class-II Restorations with the Application of a Flowable Composite as an Intermediate Layer—A Narrative Review of Clinical Trials

Journal of Functional Biomaterials
The objective of this review is to investigate the effect of an additional layer of flowable composite for cavity lining on the clinical outcome of direct posterior composite restorations. The PICO question (patient, intervention, comparison, and outcome)
Anh Duc Nguyen, Kerstin Bitter, Christian Ralf Gernhardt   +2 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Comparative Evaluation of microleakage of Bulk-fill and Posterior Composite Resins Using the Incremental Technique and a Liner in Cl II Restorations

Journal of Islamic Dental Association of Iran, 2018
Background and Aim: In recent years there has been a surge in the use of tooth-colored restorations. However, the polymerization shrinkage of these materials can form gaps, resulting in microleakage.
Samaneh Doustfateme, Kazem Khosravi, Somayeh Hosseini   +2 more
doaj  

Correlation between Periodontitis and Gastritis Induced by Helicobacter pylori: A Comprehensive Review

Microorganisms
The goal of this comprehensive review was to verify if the prevalence of Helicobacter pylori (Hp) bacteria in patients with dyspepsia is higher in the oral cavity of periodontal or non-periodontal patients.
Martina Maurotto, Liliana Gavinha Costa, Maria Conceição Manso, Grace Anne Mosley, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes, Filipe Castro   +6 more
doaj   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Gingival microleakage in class II composite restorations using different flowable composites as liner: an in vitro evaluation

Caspian journal of dental research, 2015
Introduction: One of the main disadvantages of composites is marginal microleakage using flowable composites as a liner beneath composite restorations has been recommended to reduce microleakage.
Neda Lotfi, Behnaz Esmaeili, Ghazaleh Ahmadizenouz, Ali Bijani, Hadi Khadem   +4 more
doaj  

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Effect of Storage Media on the Solubility of Commercially Available Calcium Hydroxide Cements. A Clear Guideline for Dentists

Journal of Islamic International Medical College, 2017
Objective: The objective of this study was to evaluate the influence of storage media on the solubility of four different commercially available calcium hydroxide cements.
Shahreen Zahid , Samie Qadir , Asfia Saeed , Muhammad Kaleem , Haroon Ahmed Khan
doaj