Results 101 to 110 of about 94,461 (309)

Effect of a CO2 Laser on the Inhibition of Root Surface Caries Adjacent to Restorations of Glass Ionomer Cement or Composite Resin: An In Vitro Study

open access: yesThe Scientific World Journal, 2015
This study investigated the effect of CO2 laser irradiation on the inhibition of secondary caries on root surfaces adjacent to glass ionomer cement (GIC) or composite resin (CR) restorations.
L. C. Daniel   +6 more
doaj   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

open access: yesAdvanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma   +9 more
wiley   +1 more source

Reduction of discrepancies between students and instructors in the assessment of practical tasks through structured evaluation sheets and peer feedback

open access: yesScientific Reports
The aim of this study was to reduce discrepancies between students and instructors in a preclinical dental course by employing structured peer feedback based on a detailed evaluation sheet. In a crossover study of dental students (n = 32), which compared
Mozhgan Bizhang   +5 more
doaj   +1 more source

Cavity preparation machine for the standardization of in vitro preparations

open access: yesBrazilian Oral Research, 2008
Several in vitro studies employ the confection of cavity preparations that are difficult to standardize by means of manual high speed handpieces. This study presents the development of a cavity preparation machine designed to standardize in vitro cavity ...
Carlos José Soares   +3 more
doaj   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu   +17 more
wiley   +1 more source

Preparaciones conservadoras para el tratamiento de lesiones cariosas Clase III Conservative preparations for the treatment of Class III caries lesions

open access: yesRevista de la Asociación Odontológica Argentina, 2010
Resumen La evolución de los materiales dentales revolucionó la indicación de procedimientos restauradores estéticos; así mejoraron la práctica odontológica, modificando los conceptos de preparaciones cavitarias y permitiendo una mayor conservación de ...
Juan Carlos Pontons   +2 more
doaj  

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

open access: yesAdvanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang   +8 more
wiley   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang   +3 more
wiley   +1 more source

Additive Manufactured Magnetoelectric Wireless Retainer as the Periodontal Remodeler for Post‐Orthodontic Tissue Reconstruction and Relapse‐Inhibition

open access: yesAdvanced Science, EarlyView.
Orthodontic relapse persists as a 120‐year challenge, as traditional retainers fail to remodel tissue, causing lifelong dependence. This study demonstrates a flexible magnetoelectric retainer (FMOR) enabling wireless periodontal remodeling. FMOR cues shift periodontal ligament cell (PDLC) paracrine signaling, promoting M2 macrophages, osteogenic ...
Haoqi Lei   +9 more
wiley   +1 more source

Stiffness‐Tunable Neurotentacles for Minimally Invasive Implantation and Long‐Term Neural Activity Recordings

open access: yesAdvanced Science, EarlyView.
A hydraulically actuated “Neurotentacle” probe offers tunable stiffness for precise implantation into the deep brain without rigid shuttles or dissolvable coatings. It stiffens during insertion to penetrate tissue and softens afterward to minimize damage and enable stable long‐term recordings.
Yang Wang   +8 more
wiley   +1 more source

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