Results 111 to 120 of about 94,461 (309)

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

open access: yesAdvanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu   +7 more
wiley   +1 more source

Carious dentine removal: current approach [PDF]

open access: yesRGO: Revista Gaúcha de Odontologia, 2008
Dentistry is renewed day after day through the results of qualified researches. The approach as regards carious dentin removal is goingthrough questioning and innovation.
Germana Coeli de Farias Sales   +4 more
doaj  

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

open access: yesAdvanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li   +5 more
wiley   +1 more source

An Osteoconductive Janus Hydrogel with Full Barrier Protection and Adaptable Degradation Properties for Superior Bone Regeneration

open access: yesAdvanced Science, EarlyView.
The filler‐barrier hydrogel system developed by dual‐network Janus structural strategy breaks through the difficulty of a single hydrogel to combine barrier protection with bone regeneration, and realizes the regeneration‐material degradation adaptation for the field of mandibular regeneration.
Yanhui Lu   +14 more
wiley   +1 more source

Assessment of a conservative approach for restoration of extensively destroyed posterior teeth

open access: yesJournal of Applied Oral Science
Extensive restorations in posterior teeth always bring doubts to the clinicians regarding the best protocol, mainly when structures of reinforcement were lost. Objective This study aimed to evaluate the effect of beveling on the fracture resistance and
José MONDELLI   +5 more
doaj   +1 more source

Directed Self‐Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Magnetically guided bioceramic nanoparticles (“CalBots”) achieve deep dentinal tubule occlusion via directed self‐assembly under externally applied magnetic field. Various visualization techniques and a novel mouse behavioral assay indicate that CalBot‐induced plugs may reduce dentinal sensitivity, offering a promising strategy for future dentin ...
Shanmukh Peddi   +6 more
wiley   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration

open access: yesAdvanced Science, EarlyView.
A wearable electrochemical biosensor integrated into a smart mouthguard enables the non‐invasive detection of salivary MMP‐8 for early monitoring of periodontal inflammation. Featuring a molecularly imprinted polymer‐based sensing layer, the platform offers high cytokine selectivity and impedance‐driven sensitivity. Combining wireless connectivity with
Sangheon Jeon   +10 more
wiley   +1 more source

Comparison of Dentin Permeability After Tooth Cavity Preparation with Diamond Bur and Er:YAG Laser

open access: yesFrontiers in Dentistry, 2016
Objectives: The aim of this study was to compare the permeability of dentin after using diamond bur and Er:YAG laser. Materials and Methods: Seventy-two recently extracted, intact, and restoration-free human permanent molars were used in this study. The
Masoumeh Hasani Tabatabaei   +10 more
doaj  

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