Results 191 to 200 of about 183,401 (351)

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Thymidine Phosphorylase Inhibitory Potential and Molecular Docking Studies of Secondary Metabolites Isolated From Fernandoa adenophylla (Wall. ex G. Don) Steenis

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT This study investigates the potential of Fernandoa adenophylla, a South American plant, as a reservoir of compounds with thymidine phosphorylase (TP) inhibitory activity. Through a comprehensive approach combining in vitro assays and molecular docking analysis, we isolated and characterized bioactive compounds from F.
Abdur Rauf   +11 more
wiley   +1 more source

Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin   +8 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

High‐Precision, Low‐Threshold Neuromodulation With Ultraflexible Electrode Arrays for Brain‐to‐Brain Interfaces

open access: yesExploration, EarlyView.
Traditional neuromodulation using rigid electrodes has been limited by low precision, large stimulating currents, and the risk of tissue damage. In this work, we developed a biocompatible flexible electrode array that allows for both neural recording of spike firings and high‐precision, low‐threshold stimulation for neuromodulation.
Yifei Ye   +16 more
wiley   +1 more source

The Role of Machine Learning to Detect Occult Neck Lymph Node Metastases in Early‐Stage (T1‐T2/N0) Oral Cavity Carcinomas

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective Oral cavity carcinomas (OCCs) represent roughly 50% of all head and neck cancers. The risk of occult neck metastases for early‐stage OCCs ranges from 15% to 35%, hence the need to develop tools that can support the diagnosis of detecting these neck metastases.
Stefania Troise   +12 more
wiley   +1 more source

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