Results 261 to 270 of about 144,999 (364)

Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

open access: yesExploration, EarlyView.
1. Caffeic acid (CA) is a novel senomorphic. 2. Annexin A5 is the direct protein target of CA in senescent cells. 3. The covalent binding of CA to Annexin A5 protein triggers its degradation, PKCθ deactivation, and the inhibition of the NF‐κB inflammatory pathway. 4. CA effectively alleviates inflammation and lung fibrosis in mouse model.
Yinhua Zhu   +14 more
wiley   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Effects of Galilean Loupes on Dental Students' Posture and Cavity Preparation Quality [PDF]

open access: hybrid
Júlia Margato Pazos   +2 more
openalex   +1 more source

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

open access: yesAdvanced Genetics, EarlyView.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

Synthetic hydroxyapatite: a perfect substitute for dental enamel in biofilm formation studies. [PDF]

open access: yesSci Rep
Dudek J   +12 more
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

open access: yesIbrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma   +3 more
wiley   +1 more source

The Integration of Micro-CT Imaging and Finite Element Simulations for Modelling Tooth-Inlay Systems for Mechanical Stress Analysis: A Preliminary Study. [PDF]

open access: yesJ Funct Biomater
Nikolova N   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy