Results 31 to 40 of about 40,992 (257)

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Effect of nano-hydroxyapatite incorporation on the immediate and long-term bond stability of a one-step self-etch adhesive [PDF]

Journal of Dental Materials and Techniques
Objective: This study evaluated the effect of incorporating nano-hydroxyapatite (nHAp) at various concentrations on the immediate and long-term bond strength of a one-step self-etch adhesive to dentin.Methods: A total of 100 sound maxillary central ...
Bhanu Pratap Valluri, Madhu Varma Kanumuri, Girija Sajjan, Kalyan Satish Rajulapati, Venkata Karteek Varma Penmatsa, Jagapathi Babu Mavidi   +5 more
doaj   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

Physicochemical, Biological, and Antibacterial Properties of Four Bioactive Calcium Silicate-Based Cements

Pharmaceutics, 2023
Calcium silicate-based cement (CSC) is a pharmaceutical agent that is widely used in dentistry. This bioactive material is used for vital pulp treatment due to its excellent biocompatibility, sealing ability, and antibacterial activity.
Yu-Ji Jang, Yu-Jin Kim, Huong Thu Vu, Jeong-Hui Park, Seong-Jin Shin, Khandmaa Dashnyam, Jonathan C. Knowles, Hae-Hyoung Lee, Soo-Kyung Jun, Mi-Ran Han, Joon-Haeng Lee, Jong-Soo Kim, Jong-Bin Kim, Jung-Hwan Lee, Ji-Sun Shin   +14 more
doaj   +1 more source

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Cytotoxicity and biocompatibility of Zirconia (Y-TZP) posts with various dental cements

Restorative Dentistry & Endodontics, 2016
Objectives Endodontically treated teeth with insufficient tooth structure are often restored with esthetic restorations. This study evaluated the cytotoxicity and biological effects of yttria partially stabilized zirconia (Y-TZP) blocks in combination ...
Hyeongsoon Shin, Hyunjung Ko, Miri Kim
doaj   +1 more source

Analysis of stresses during the polymerization shrinkage of self-curing resin cement in indirect restorations: A finite-element study

Indian Journal of Dental Research, 2014
Background: Adhesive cementation is essential for the longevity of indirect esthetic restorations. However, polymerization shrinkage of resin cement generates stress, which may cause failures in the tooth-restoration interface.
Tulimar M Cornacchia, Guilherme C Silva, Claudia S Magalhaes, Allyson N Moreira, Estevam B Las Casas   +4 more
doaj   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Comparison of Luting Cement Solubility: A Narrative Review

Dentistry Journal
Background: Dental restoration success relies on the physical properties of luting cements. Luting cements fill the space between teeth and the restoration, provide retention and protection from occlusal forces, and act as a barrier to microleakages in ...
Deok Yong Kim, Nona Aryan, Nathaniel C. Lawson, Kyounga Cheon   +3 more
doaj   +1 more source