Results 41 to 50 of about 316,514 (314)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Dental treatment and risk of variant CJD - a case control study [PDF]

open access: yes, 2007
Objective: Knowledge of risk factors for variant CJD (vCJD) remains limited, but transmission of prion proteins via re-useable medical devices, including dental instruments, or enhanced susceptibility following trauma to the oral cavity is a concern ...
Everington, D.   +11 more
core   +1 more source

Development of Handy Dental Surveyor.

open access: yesTHE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN, 1993
A small portable surveyor, easy to use, was newly devised. The surveyor is essentially a parallelometer, an instrument used for determining the relative parallelism of two or more surfaces of the teeth or other parts of the dental cast. The characteristic structures of this instrument is as follows: The vertical standard is directly connected to the ...
Ai, Minoru, Nakamura, Kazuo
openaire   +3 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Development and evaluation of an English learning system using smartphones in Japanese dental hygiene education

open access: yes, 2019
Purpose: To develop and evaluate the effects of an English learning system using smartphones in Japanese dental hygiene education. Methods: Forty-three third-year undergraduate university dental hygiene students took a preliminary examination and then ...
Takenouchi, Akane   +4 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Benefits and risks of direct access to treatment by dental care professionals:a rapid evidence review [PDF]

open access: yes, 2012
Over 100 research dental and other health-related papers were identified as relevant for this review of direct access. The quality of the evidence regarding direct access issues to dental care practitioners was varied but as a whole of moderately good ...
MacGillivray, Stephen; id_orcid   +2 more
core  

Immunohistochemical study for the expression of leukocyte adhesion molecules, and FGF23 and ACE2 in P. gingivalis LPS-induced diabetic nephropathy

open access: yesBMC Nephrology, 2021
Objective The present study aims to examine the expression of leukocyte adhesion molecules and renal metabolic factors in diabetic mouse kidneys with periodontal pathogen Pg-LPS-induced nephropathy.
Koichiro Kajiwara   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The modified dental anxiety scale: UK general public population norms in 2008 with further psychometrics and effects of age

open access: yes, 2009
BACKGROUND: The Modified Dental Anxiety Scale (MDAS) is a brief, self-complete questionnaire consisting of five questions and summed together to produce a total score ranging from 5 to 25.
Robinson, Peter G   +11 more
core   +1 more source

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