Results 101 to 110 of about 50,135 (262)

Fgf9 promotes incisor dental epithelial stem cell survival and enamel formation

open access: yesStem Cell Research & Therapy
Background Understanding the role of cytokines in tooth development is critical for advancing dental tissue engineering. Fibroblast growth factor 9 (FGF9) is the only FGF consistently expressed throughout dental epithelial tissue, from the initiation of ...
Lingyun Tang   +11 more
doaj   +1 more source

The influence of flap design on the relevance of biomaterials in regenerative periodontal surgery

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The aim of this systematic review was to explore whether the benefits of biomaterials in periodontal regenerative/reconstructive surgery are affected by the type of flap employed. The study addresses the existing gap in the evidence to substantiate the beneficial effect of minimal invasive periodontal surgical approach compared to a
Payvand Menhadji   +2 more
wiley   +1 more source

Tracing the evolution of root coverage: Clinical milestones leading to a minimally invasive era

open access: yesJournal of Periodontology, EarlyView.
Abstract Over the past several decades, periodontal plastic surgery has undergone a remarkable transformation, particularly in the field of root coverage procedures. This review traces the historical evolution of surgical techniques, from the early use of pedicle flaps and free gingival grafts (FGGs) to the development of bilaminar approaches ...
Lorenzo Tavelli   +6 more
wiley   +1 more source

A retrospective cohort study comparing periodontal regeneration using fibroblast growth factor‐2 versus autologous bone graft

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Fibroblast growth factor‐2 (FGF‐2) is a novel agent utilized in periodontal regeneration therapy. However, its clinical efficacy compared with autologous bone graft (ABG), a long‐established treatment, remains unclear. This study aimed to compare the clinical outcomes of FGF‐2 and ABG and to assess the impact of patient background ...
Toshiki Matsumoto   +11 more
wiley   +1 more source

Mineral‐targeted alkaline phosphatase improves bone graft‐mediated alveolar bone defect healing in mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri   +4 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira   +9 more
wiley   +1 more source

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