Results 81 to 90 of about 63,507 (333)

Reptile enamel matrix proteins: Selection, divergence, and functional constraint.

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2019
The three major enamel matrix proteins (EMPs): amelogenin (AMEL), ameloblastin (AMBN), and enamelin (ENAM), are intrinsically linked to tooth development in tetrapods. However, reptiles and mammals exhibit significant differences in dental patterning and
Omar Alazem, John Abramyan
semanticscholar   +1 more source

Non‐RASopathy Genetic Syndromes Identified as the Molecular Cause of Disease in Patients Previously Diagnosed With Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim, Alexsandra Christianne Malaquias, Debora Romeo Bertola, Raissa Carneiro Rezende, Laurana De Polli Cellin, Lucas Vieira Lacerda Pires, Ana Maria Santillan‐Vasconez, Antônio Marcondes Lerario, Renata da Cunha Scalco, Alexander Augusto de Lima Jorge   +9 more
wiley   +1 more source

Amelogenin Peptide Extract Increases Differentiation and Angiogenic and Local Factor Production and Inhibits Apoptosis in Human Osteoblasts [PDF]

, 2013
Enamel matrix derivative (EMD), a decellularized porcine extracellular matrix (ECM), is used clinically in periodontal tissue regeneration. Amelogenin, EMD’s principal component, spontaneously assembles into nanospheres in vivo, forming an ECM complex ...
Almaguer-Flores, Argelia, Boyan, Barbara D., Gemperli, Anja C., Hyzy, Sharon L., Mauth, Corinna, Olivares-Navarrete, Rene, Schwartz, Zvi   +6 more
core   +2 more sources

Hen's teeth with enamel cap: from dream to impossibility

BMC Evolutionary Biology, 2008
Background The ability to form teeth was lost in an ancestor of all modern birds, approximately 100-80 million years ago. However, experiments in chicken have revealed that the oral epithelium can respond to inductive signals from mouse mesenchyme ...
Girondot Marc, Delgado Sidney C, Sire Jean-Yves   +2 more
doaj   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

Molar incisor hypomineralisation: current knowledge and practice

International Dental Journal, EarlyView., 2020
Background Molar incisor hypomineralisation (MIH) is a common developmental dental condition that presents in childhood. Areas of poorly formed enamel affect one or more first permanent molars and can cause opacities on the anterior teeth. MIH presents a variety of challenges for the dental team as well as functional and social impacts for affected ...
Helen D. Rodd, Anna Graham, Niecoo Tajmehr, Laura Timms, Noren Hasmun   +4 more
wiley   +1 more source

Particle motion and stain removal during simulated abrasive tooth cleaning [PDF]

, 2007
Stain removal from teeth is important both to prevent decay and for appearance. This is usually achieved using a filament-based toothbrush with a toothpaste consisting of abrasive particles in a carrier fluid.
Addy, Allen, Barbakow, Baxter, Condon, Dawson, Forward, Harrington, Heath, Hefferren, Jardret, Joiner, Lewis, Lewis, MacPherson, Manly, Phaneuf, R. Lewis, R.S. Dwyer-Joyce, S.C. Barber, Sheen, Stookey, White   +22 more
core   +2 more sources

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Advances of Proteomic Sciences in Dentistry [PDF]

, 2016
Applications of proteomics tools revolutionized various biomedical disciplines such as genetics, molecular biology, medicine, and dentistry. The aim of this review is to highlight the major milestones in proteomics in dentistry during the last fifteen ...
Bartlett, Campisi, Dannies, Huynh, Ihtesham Rehman, Jágr, Matinlinna, Mjör, Muhammad Zafar, Rabia Rehman, Sana Zohaib, Shariq Najeeb, Tete, Wu, Yamazoe, Yan, Yu, Zohaib Khurshid   +17 more
core   +2 more sources

306 Intraoral Spectroscopy for the Identification and Study of Molar Hypomineralization

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: Molar hypomineralization (MH) is a highly prevalent dental disease that leads to rapid enamel decay even with preventative measures. While the harm is apparent, the etiology of the condition is not. Further, MH is difficult to study due
Sarah Boyer, Ray Jurado, Ashlee Cosantino, Azza Ahmed, Derk Joester   +4 more
doaj   +1 more source