Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Evaluation of dental ages of children with type I diabetes using different dental age estimation methods: a retrospective cohort study. [PDF]
Özdemir Çelik DS, Belevcikli M.
europepmc +1 more source
An important change to the American Dental Association Principles of Ethics and Code of Professional Conduct [PDF]
Adam A. Edwards
openalex +1 more source
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang +10 more
wiley +1 more source
Attitudes and perceptions of dental students and interns toward AI in dentistry: a cross-sectional survey in a Saudi population. [PDF]
Alazmah AS +6 more
europepmc +1 more source
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
Global Trends in Non-Technical Skills Research in Dental Education: Bibliometric Review and a Curricular Case Study. [PDF]
Arunratanothai T +6 more
europepmc +1 more source
Code of Medical Ethics: Guidelines of Bangladesh Medical and Dental Council (BMDC)
The Editor
openalex +2 more sources
Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui +8 more
wiley +1 more source
Dental Practitioners' Knowledge and Attitude Towards Ultrasonography: A Cross-Sectional Study at a South African University. [PDF]
Simpson J +3 more
europepmc +1 more source

