Results 161 to 170 of about 73,396 (339)
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu+11 more
wiley +1 more source
BONE QUALITY IN PATIENTS RECEIVING ENDOSSEOUS DENTAL IMPLANTS
Ira H. Orenstein+4 more
openalex +1 more source
Prefrontal FGF1 Signaling is Required for Accumbal Deep Brain Stimulation Treatment of Addiction
This research delineates that a cortical‐accumbal pathway and local FGF1 signaling in the medial prefrontal cortex are critical for NAc‐DBS to be effective in altering morphine CPP. These findings demonstrate a top‐down motif to regulate the therapeutic effects of subcortical DBS on addiction and support the potential for addiction treatments involving
Wan‐Kun Gong+11 more
wiley +1 more source
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du+8 more
wiley +1 more source
The Influence of First-Stage Mobility on the Osseointegration of Dental Implants
Frank R. Lauciello+7 more
openalex +1 more source
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian+11 more
wiley +1 more source
Abstract Antlers are the most conspicuous trait of cervids and have been used in the past to establish a classification of their fossil and living representatives. Since the availability of molecular data, morphological characters have generally become less important for phylogenetic reconstructions.
Nicola S. Heckeberg+2 more
wiley +1 more source