Results 31 to 40 of about 141,637 (333)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Impact of Ninjin’yoeito on frailty and short life in klotho-hypomorphic (kl/kl) mice

Frontiers in Pharmacology, 2022
With the recent aging of society, the prevention of frailty has become an important issue because people desire both a long and healthy lifespan. Klotho-hypomorphic (kl/kl) mice are known to show phenotypes of premature aging.
Haruka Amitani, Haruka Amitani, Shigeki Chiba, Marie Amitani, Marie Amitani, Seiwa Michihara, Risa Takemoto, Likun Han, Nina Fujita, Ryuji Takahashi, Akio Inui   +10 more
doaj   +1 more source

Potential causes of mortality for horseshoe crabs (Limulus polyphemus) during the biomedical bleeding process [PDF]

, 2006
Biomedical companies catch and bleed horseshoe crabs for the production of Limulus amebocyte lysate (LAL), a product used for protecting public health (Berkson and Shuster, 1999).
Berkson, Jim, Hurton, Lenka
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

The effect of noise exposure on the vestibular systems of dental technicians

Noise and Health, 2019
Background: Noise exposure is the primary cause of acquired hearing loss in several occupational settings, including dental laboratories and clinics. However, the impact of noise exposure on the vestibular system is not as well researched.
Safa Alqudah
doaj   +1 more source

A MODEL FOR INTEGRATED SOFTWARE TO IMPROVE COMMUNICATION POLICY IN DENTAL TECHNICAL LABS [PDF]

Journal of IMAB, 2017
Introduction: Integrated marketing communications (IMC) are all kinds of communications between organisations and customers, partners, other organisations and society.
Minko M. Milev, Emilia P. Georgieva, Neli M. Ermenlieva, Juliyan V. Kostadinov, Silviya N. Angelova, Plamen S. Rusev   +5 more
doaj   +1 more source

Use of Interdisciplinary Education to Foster Familiarization among Health Professionals [PDF]

, 1986
This paper describes a pilot interdisciplinary experience between the dental hygiene and medical technology programs at Marquette University. It was designed, in part, to familiarize dental hygiene students with the medical technology profession ...
Laatsch-Lybeck, Linda Jean, Milson, Linda, Zimmer, Susan E.   +2 more
core   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Sociological characteristics of the current state of the laboratory phase of providing dental orthopedic treatment to the population (on the example of the Irkutsk Region)

Acta Biomedica Scientifica, 2016
Key problems of the dental laboratories in public health sector include insufficient material and technical equipment, weakly theoretically and practically trained personnel and often a mismatch between the structure and organization of the laboratories ...
N. O. Fedchishin, I. S. Kitsul
doaj   +1 more source