Results 211 to 220 of about 3,524,864 (361)

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Laboratory fabricated (indirect) composite veneers in esthetic management of severe dental fluorosis

open access: diamond, 2004
RN Ng’ang’a   +5 more
openalex   +1 more source

Shade-matching abilities of dental laboratory technicians using a commercial light source.

open access: yesJournal of Prosthodontics, 2009
T. R. Jasinevicius   +3 more
semanticscholar   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

Surface Conditioning Methods and Their Effects on Micro-Tensile Bond Strength and Micro-Chemical Properties of Glass-Infiltrated Zirconia: An In Vitro Study. [PDF]

open access: yesMed Sci Monit
Yaqoob A   +13 more
europepmc   +1 more source

Pneumoconiosis and exposures of dental laboratory technicians.

open access: yesAmerican Journal of Public Health, 1984
W. Rom   +8 more
semanticscholar   +1 more source

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