Results 241 to 250 of about 3,254,798 (316)

A Porcine Monoclonal Antibody Targeting a Conserved GP4 Epitope Protects against In Vivo Infection via the Induction of Broad‐Spectrum PRRSV Neutralization

open access: yesAdvanced Science, EarlyView.
This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen   +12 more
wiley   +1 more source

Rare Oral Manifestations of Systemic Amyloidosis: A Case Report. [PDF]

open access: yesCase Rep Hematol
Barazanji S   +2 more
europepmc   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

open access: yesAdvanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang   +19 more
wiley   +1 more source

A novel phex gene variant causes non-syndromic tooth agenesis. [PDF]

open access: yesBMC Oral Health
Pan Y   +6 more
europepmc   +1 more source

Clinical laboratory profiling and microbiological analysis of the oral cavity of dogs (Canis familiaris) with dental disorders

open access: gold
Leonardo Costa Rocha   +6 more
openalex   +1 more source

MASCC/ISOO Clinical Practice Statement: imaging and clinical laboratory tests in the diagnosis and management of medication-related osteonecrosis of the jaw. [PDF]

open access: yesSupport Care Cancer
Yarom N   +9 more
europepmc   +1 more source

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