Results 191 to 200 of about 45,435 (304)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

open access: yesThe FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma   +1 more
wiley   +1 more source

Clinical Validity of the Oral Frailty Five‐Item Checklist (OF‐5) for the Diagnosis of Oral Hypofunction

open access: yesGerodontology, EarlyView.
ABSTRACT Objective This study aimed to clinically validate the Oral Frailty Five‐item Checklist (OF‐5) by clarifying the relationship between its score and the diagnosis of oral dysfunction, as well as its association with seven sub‐items. Background Assessing oral frailty is important for preventing frailty in older adults. The recently developed OF‐5
Tomohiro Tabata   +6 more
wiley   +1 more source

Prevalence of Dental Caries in Persons With or Without Long‐Term Experience of Positive Airway Pressure‐Treated Obstructive Sleep Apnoea

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Oral dryness is common in persons with untreated obstructive sleep apnoea (OSA) as well as in those using positive airway pressure (PAP). OSA with or without PAP treatment could therefore be a risk factor of dental caries. Objectives To describe and compare the prevalence of dental caries among persons with or without PAP‐treated OSA.
H. Ahonen   +6 more
wiley   +1 more source

A re‐usable 3D‐printed training model for the endodontic management of dental trauma in immature teeth

open access: yesInternational Endodontic Journal, EarlyView.
Abstract Aim To develop a 3D‐printed model enabling treatment simulation of trauma‐related endodontic and restorative procedures like revitalization or placement of an apical plug on teeth with incomplete root formation. Methodology To generate a realistic training model suitable for trauma‐related simulations, CT‐Data sets were segmented, combined ...
Eva Maier   +7 more
wiley   +1 more source

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