Results 41 to 50 of about 7,288 (259)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Improvement of all-ceramic crowns fixation method with the use of transfer-template construction

open access: yesZaporožskij Medicinskij Žurnal, 2020
Modern practical dentistry still faces the problem regarding accurate fit of non-metallic prosthetic constructions. Such precise fit helps to minimize the effect of micro-leakage in the area of the interface, reduces the risk of decementation and ...
A. V. Bokoch   +2 more
doaj   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

open access: yesAdvanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi   +15 more
wiley   +1 more source

Impact of finish line designs on the adaptation of ceramic fixed dental prostheses: a systematic review and network meta-analysis

open access: yesBMC Oral Health
Background Insufficient marginal and internal adaptation can lead to secondary caries, pulp infection, periodontal disease, and tooth loss. This network meta-analysis (NMA) assessed the impact of various finish line designs on the marginal and internal ...
Adrienn Pál   +9 more
doaj   +1 more source

Marginal adaptation of provisional crowns made of acrylic and bisacrylic resins using different impression materials

open access: yesBrazilian Journal of Oral Sciences, 2019
Aim: To evaluate the marginal adaptation of provisional crowns made of acrylic and bisacrylic resins using different impression materials. Methods: a metal die and a matrix applied through a direct technique were used to fabricate the specimens.
Camilla Lopes Cerqueira   +3 more
doaj   +1 more source

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

open access: yesAdvanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun   +10 more
wiley   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

Comparative Analysis of the Marginal Fit and Internal Adaptation of CAD-CAM-Fabricated Versus Conventionally Fabricated Ceramic Crowns: A Systematic Review

open access: yesJournal of Pharmacy and Bioallied Sciences
This systematic review compared the marginal fit and internal adaptation of ceramic crowns and fixed dental prostheses (FDPs) fabricated using CAD-CAM technology versus conventional methods.
Mohammed Ibrahim Mathar
doaj   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

open access: yesAdvanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai   +9 more
wiley   +1 more source

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