Results 71 to 80 of about 27,261 (297)
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu+9 more
wiley +1 more source
Orthodontic relapse persists as a 120‐year challenge, as traditional retainers fail to remodel tissue, causing lifelong dependence. This study demonstrates a flexible magnetoelectric retainer (FMOR) enabling wireless periodontal remodeling. FMOR cues shift periodontal ligament cell (PDLC) paracrine signaling, promoting M2 macrophages, osteogenic ...
Haoqi Lei+9 more
wiley +1 more source
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li+8 more
wiley +1 more source
Impact of adhesive and photoactivation method on sealant integrity and polymer network formation
We evaluated the influence of photoactivation method and hydrophobic resin (HR) application on the marginal and internal adaptation, hardness (KHN), and crosslink density (CLD) of a resin-based fissure sealant.
Boniek Castillo Dutra Borges+6 more
doaj +1 more source
Magnetically guided bioceramic nanoparticles (“CalBots”) achieve deep dentinal tubule occlusion via directed self‐assembly under externally applied magnetic field. Various visualization techniques and a novel mouse behavioral assay indicate that CalBot‐induced plugs may reduce dentinal sensitivity, offering a promising strategy for future dentin ...
Shanmukh Peddi+6 more
wiley +1 more source
Low shrinkage composite resins: influence on sealing ability in unfavorable C-factor cavities
The present investigation observed the sealing ability of low shrinkage composite resins in large and deep cavities, placed and photocured in one increment.
Eliza Burlamaqui Klautau+4 more
doaj +1 more source
Vertical Marginal Discrepancy of a Monolithic Zirconia Crown with Different Cement Spaces
The long-term clinical success of indirect restorations highly depends on their marginal integrity. The cement space is an element that might affect the marginal integrity, but it can be altered during the configuring of the computer-assisted designing ...
Turki Alkhallagi+4 more
doaj +1 more source
ABSTRACT Over almost two decades, young people's employment opportunities have been significantly impacted by events like the Global Financial Crisis (2008–2009) and the COVID‐19 pandemic (2020‐). Thus, underemployment has become a more pervasive and persistent feature of young people's labour market experiences. This research focuses on three forms of
Brendan Churchill
wiley +1 more source
Objective The aim of this in vitro study was to compare the effect of printing layer thickness on the marginal and internal fit of interim crowns. Material and methods A maxillary first molar model was prepared for ceramic restoration.
Mahya Hasanzade+3 more
doaj +1 more source
Early synapsids neurosensory diversity revealed by CT and synchrotron scanning
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit+6 more
wiley +1 more source