Results 51 to 60 of about 1,144 (166)

Identification of Middle Mesial Canal in Mandibular Molars Using Five Different Techniques: An In vitro Study

Journal of Pharmacy and Bioallied Sciences
Aim: The purpose of the study was to find out the incidence of the middle mesial canal in mandibular molars by using five different techniques. Materials and Methods: A total of 150 extracted human mandibular first molars were selected, and cone beam ...
Kanduri Venkata Naga Vamseekrishna, Navneet Kukreja, Mayank Sachdeva, Sindhura Ravi, Swati Chhabra, Surinder Sachdeva   +5 more
doaj   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Evaluation of surgical visualization headset in dental education for preclinical bone augmentation surgery

BMC Oral Health
Background Effective preclinical training for complex procedures, such as oral bone augmentation, demands high-fidelity visual demonstration. The conventional “display screen combined with a dental microscope” model is limited by inconsistent sightlines,
Hao Zeng, Qihang Fan, Ting Xia, Qin Zhao   +3 more
doaj   +1 more source

The Benefits of a Dental Operating Microscope for Tooth Extractions: A Case Report

Dentistry Journal
Background/Objectives: Operating microscopes are becoming increasingly common tools in dentistry and dentoalveolar surgery due to their ability to enhance procedural precision and control.
Bruno Calkovsky, Ladislava Slobodnikova, Sarah Kalmanova, Maria Janickova   +3 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Endodontic microsurgery: An overview

Dentistry and Medical Research, 2015
The concurrent development of better techniques has resulted in greater understanding of the apical anatomy, greater treatment success, and a more favorable patient response. These developments marked the beginning of the endodontic microsurgery era that
Sumangali Ananad, E Soujanya, Ananda Raju, Aravelli Swathi   +3 more
doaj   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Diagnosis of dental erosion using intraoral scanner in comparison to 3D confocal laser microscope [PDF]

Alexandria Dental Journal
Introduction: Many in vitro and in vivo techniques to diagnose and measure dental erosion are included in the literature, but none of the in vivo techniques could detect the early erosive enamel wear in microns.Objectives: The aim of this study was to ...
Aya Hassan, Rania Afifi, Wegdan M. Abdel-Fattah, Mohamed Gepreel   +3 more
doaj   +1 more source