Results 151 to 160 of about 174,232 (303)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Accuracy of five different 3D printing workflows for dental models comparing industrial and dental desktop printers. [PDF]

Clin Oral Investig, 2023
Morón-Conejo B, López-Vilagran J, Cáceres D, Berrendero S, Pradíes G.   +4 more
europepmc   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Finite element stress analysis study for stresses around mandibular implant retained overdenture MIR-OD

Journal of Baghdad College of Dentistry, 2014
Background: It has been well known that the success of mandibular implant- retained overdenture heavily depends on initial stability, retention and long term osseointegration this is might be due to optimal stresses distribution in surrounding bones ...
Raghdaa K Jassim, Ibrahim K Ibrahim
doaj  

Deep learning-based approach for 3D bone segmentation and prediction of missing tooth region for dental implant planning

Scientific Reports
Recent studies have shown that dental implants have high long-term survival rates, indicating their effectiveness compared to other treatments. However, there is still a concern regarding treatment failure.
Mohammed Al-Asali, Ahmed Yaseen Alqutaibi, Mohammed Al-Sarem, Faisal Saeed   +3 more
doaj   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

'Invisible' orthodontics by polymeric 'clear' aligners molded on 3D-printed personalized dental models. [PDF]

Regen Biomater, 2022
Yu X, Li G, Zheng Y, Gao J, Fu Y, Wang Q, Huang L, Pan X, Ding J.   +8 more
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

The effects of clinical dental status on eating difficulty and oral health-related quality of life in an older Chinese population.

, 2007
Most studies about the relationships between dental status and eating difficulty and food choice have been done in Western countries. Their foods and methods of preparation differ from Eastern countries.
Zeng, X.
core  

Influence of Implant Impression Methods, Polymer Materials, and Implant Angulation on the Accuracy of Dental Models. [PDF]

Polymers (Basel), 2022
Djurovic Koprivica D, Puskar T, Budak I, Sokac M, Jeremic Knezevic M, Maletin A, Milekic B, Vukelic D.   +7 more
europepmc   +1 more source