Matrix Stiffness Induces Endothelial Network Senescence
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source
Analysis of Three-Dimensional Tooth Movement: A Comparative Study Between Digital Dental Models and Craniofacial Models. [PDF]
Kubota R, Fushima K, Arisaka H.
europepmc +1 more source
Impact of Aging on the Accuracy of 3D-Printed Dental Models: An In Vitro Investigation. [PDF]
Joda T, Matthisson L, Zitzmann NU.
europepmc +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
wiley +1 more source
A Comparison of the Accuracy of Two Non-dental 3D Printers and a Standard Dental 3D Printer for Printing Dental Models: An In Vitro 3D Analysis. [PDF]
Chiang S +4 more
europepmc +1 more source
Comparison of Presurgical Dental Models Manufactured with Two Different Three-Dimensional Printing Techniques. [PDF]
Metlerski M +4 more
europepmc +1 more source
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen +10 more
wiley +1 more source
Evaluating the precision and accuracy of digital dental models with a low-cost structured light device. [PDF]
Stuani VT +5 more
europepmc +1 more source
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li +13 more
wiley +1 more source
Experimental study on dimensional variations of 3D printed dental models based on printing orientation. [PDF]
Perlea P +3 more
europepmc +1 more source

