Results 51 to 60 of about 1,123,990 (335)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Computer Modelling of Dental Plaque in Relation to Dental Caries

Microbial Ecology in Health & Disease, 1990
The complex interplay of diffusion and reaction during a cariogenic challenge to the tooth, after sugar ingestion, is considered in terms of mathematical modelling of the dental plaque using finite-difference computer techniques. A discussion of some of the factors which might be included in a model is followed by a brief review of previous models and ...
openaire   +2 more sources

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

A Model for Dental Practice in the 21st Century

American Journal of Public Health, 2011
The dental profession is responsible for the prevention, diagnosis, and treatment of diseases and disorders of the oral cavity and related structures. Although the majority of the US population receives excellent oral health care, a significant portion is unable to access regular care.
Kayleigh Eaves, Ira B. Lamster
openaire   +4 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu, Krish Shah, Cristina D. Toedebusch, Ashley Hess, Rachel Richardson, Emmanuel Mignot, Suzanne E. Schindler, Tammie L. S. Benzinger, Shaney Flores, Jason Hassenstab, Chengjie Xiong, John C. Morris, David M. Holtzman, Brendan P. Lucey   +13 more
wiley   +1 more source

Quality of models supplied to dental laboratories for the fabrication of partial removable denture framework

RGO: Revista Gaúcha de Odontologia, 2020
Objective The aim of this study was to evaluate the models and plannings of metallic framework of removable partial prosthesis sent to dental laboratories in the city of Recife.
Luma de Vasconcelos MENEZES, Thais Carine SILVA, Catia Maria Fonseca GUERRA, Renata CIMÕES, Bruna de Carvalho Farias VAJGEL   +4 more
doaj   +1 more source

A Sequential Framework for Detection and Classification of Abnormal Teeth in Panoramic X-rays [PDF]

arXiv, 2023
This paper describes our solution for the Dental Enumeration and Diagnosis on Panoramic X-rays Challenge at MICCAI 2023. Our approach consists of a multi-step framework tailored to the task of detecting and classifying abnormal teeth. The solution includes three sequential stages: dental instance detection, healthy instance filtering, and abnormal ...
arxiv  

Staffing Model for Dental Wellness and Readiness [PDF]

Military Medicine, 2004
Oral health is an integral part of general health. Previous research has shown that untreated oral conditions can result in increased rates of disease and nonbattle injury for deployed soldiers. The purpose of this study was to develop models for U.S. Army dental wellness and readiness using a multivariate regression analysis approach.
Kenn Finstuen, Stephen D. Larsen, Scott A. Johnson, Jeffrey G. Chaffin, Larry G. Rothfuss   +4 more
openaire   +3 more sources

Effects of Pharmacologic and Nonpharmacologic Interventions for the Management of Sleep Problems in People With Fibromyalgia: Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

Arthritis Care &Research, EarlyView.
Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson, Mari Imamura, Clare Robertson, Daniel Whibley, Lorna Aucott, Katie Gillies, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole K. Y. Tang, Gary J. Macfarlane, Miriam Brazzelli   +11 more
wiley   +1 more source