Results 51 to 60 of about 7,351,298 (291)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Efficiency and Accuracy of Three-Dimensional Models Versus Dental Casts: A Clinical Study

Turkish Journal of Orthodontics, 2019
Objective:The aim of this study was to compare the accuracy of digital and plaster model methods and the time required for analysis.Methods:A total of 30 subjects (20 females, 10 males; mean age, 14.36±6.30 years), who required plaster models for the ...
Hakan Yılmaz, Fethiye Çakmak Özlü, Carmen Karadeniz, Ersan İlsay Karadeniz   +3 more
doaj   +1 more source

Cost-Effective Full-Color 3D Dental Imaging Based on Close-Range Photogrammetry

Bioengineering, 2023
Dental imaging plays a crucial role in clinical dental practice. Conventional 2D dental imaging serves general-purpose tasks, such as patient documentation, while high-precision 3D dental scanning is tailored for specialized procedures, such as ...
Bin Yang, Jennifer Schinke, Amir Rastegar, Melikhan Tanyeri, John A. Viator   +4 more
doaj   +1 more source

Challenges in Dental Statistics: Data and Modelling

, 2022
The aim of this work is to present the reflections and proposals derived from the first Workshop of the SISMEC STATDENT working group on statistical methods and applications in dentistry, held in Ancona (Italy) on 28th September 2011. STATDENT began as a forum of comparison and discussion for statisticians working in the field of dental research in ...
Matranga D, CASTIGLIA, Paolo Giuseppino, SOLINAS, Maria Giuliana   +2 more
openaire   +5 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Accuracy of 3D Printed Model Acquired from Different Types of Intra Oral Scanners and 3D Printers

Journal of Pharmacy and Bioallied Sciences
ObjectiveThe aim of this study was to verify the influence of different types of intraoral scanners and 3D printers on the accuracy of printed models in comparison to plaster models obtained from conventional impressions.
Niras Soniya, Chokhani Dishita, Jadhao Tanvi A, Bandgar Shreyas T, Bayaskar Surbhi G   +4 more
doaj   +1 more source

RANKL neutralisation prevents osteoclast activation in a human ameloblastoma-bone model

Journal of Tissue Engineering, 2022
Ameloblastoma is a benign, locally invasive epithelial odontogenic neoplasm of the jaw. Treatment of choice is jaw resection, often resulting in significant morbidity.
Judith Pape, Deniz Bakkalci, Rawiya Al Hosni, Benjamin S Simpson, Kristiina Heikinheimo, Stefano Fedele, Umber Cheema   +6 more
doaj   +1 more source

Analysis of the Degradation of a Model Dental Composite [PDF]

Journal of Dental Research, 2008
Dental composites undergo material property changes during exposure to the oral environment and may release compounds of potential toxicity, such as bisphenol A. Degradation of dental composites was studied in a simplified overlayer model in which bisphenol A diglycidyl methacrylate (BisGMA) was covalently bound to a porous silicon oxide surface.
P J, Koin, A, Kilislioglu, M, Zhou, J L, Drummond, L, Hanley   +4 more
openaire   +2 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Oral Health-Related Complications of Breast Cancer Treatment: Assessing Dental Hygienists’ Knowledge and Professional Practice

, 2014
Purpose: Approximately 200,000 women are diagnosed with breast cancer in the U.S. every year. These patients commonly suffer from oral complications of their cancer therapy.
Inglehart, Marita Rohr, Taichman, L. Susan, Gomez, Grace   +2 more
core   +1 more source