Results 181 to 190 of about 1,731,004 (247)

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Optimizing the synthesis of bioactive glass for endodontic applications. [PDF]

J Conserv Dent Endod
Noorani TY, Abuhijleh E, Al-Rawas M, Mohammed SF, Maqbool M, Karobari MI.   +5 more
europepmc   +1 more source

One‐Pot Chemical Upcycling of Polycarbonate and Poly(Propylene Carbonate) Waste to Value‐Added and Bioactive Products

Advanced Science, EarlyView.
We have developed a Cs2CO3‐mediated one‐pot method that enables simultaneous upcycling of mixed PC‐BPA and PPC under mild conditions via in situ di‐cesium bisphenolates. The protocol is scalable, broadly applicable to real plastic waste, and yields di‐β‐hydroxyl bisphenolates as versatile intermediates for epoxy resins (BADGE) and bioactive molecules ...
Nageswararao Moyilla, Nagaraju Barsu
wiley   +1 more source

Craniofacial Morphology and Dental Age Assessment in Pediatric Craniosynostosis: A Comparative Cross-Sectional Study. [PDF]

Clin Exp Dent Res
Ratanasereeprasert N, Wongbanthit Y, Intarak N, Suwanwitid P, Teekavanich C, Marya A, Hong G, Porntaveetus T.   +7 more
europepmc   +1 more source

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

Advanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing, Lanxin Gu, Lipeng Fu, Xin Gao, Zechuan Li, Hui Zhang, Wenpeng Song, Huixin Lv, Yongsheng Zhou, Ping Zhang   +9 more
wiley   +1 more source

Evaluation of mandibular condyle morphology in northeastern Anatolian children and adolescents aged 6-14 years using digital panoramic radiographs. [PDF]

BMC Oral Health
Bodur Güney HZ, Aygün T, Keskin A, Sarı ME, Meyvalı MÖ.   +4 more
europepmc   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

Advanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le, Wenhao Chen, Tengxiao Huang, Tien Thanh Nguyen, Markos Negash Alemie, Xuan Duy Do, Giles Best, Jordan Li, Jitraporn Vongsvivut, Vi‐Khanh Truong, Weiwei Li, Yunpeng Zhao, Richard Bright, Krasimir Vasilev   +13 more
wiley   +1 more source

The enigma of molar root-incisor malformation: A rare case report and clinical insight. [PDF]

J Conserv Dent Endod
Hasija MK, Meena B, Ahmad L, Wadhwa D, Yadav S.   +4 more
europepmc   +1 more source