Results 81 to 90 of about 1,731,004 (247)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Nuevo ejemplar de Cuvieronius hyodon (Proboscidea: Gomphotheriidae) del Pleistoceno de Costa Rica

open access: yesRevista de Biología Tropical, 1998
A lower mastodont molar was found in Nacaome river, Nicoya, Guanacaste, Costa Rica. It is a Pleistocene specimen of Cuvieronius hyodon. C. hyodon and Haplomastodon waringi, mountain and savanna mastodonts respectively, have been found in the same place ...
Rafael Acuña-Mesén   +1 more
doaj  

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Effect of emotional stress on cold structural and functional state dental pulp rats

open access: yesКубанский научный медицинский вестник, 2015
In the experiment established the influence of emotional and cold stress not only on metabolic changes, but also structural changes in the dental pulp.
I. G. Ostrovskaya   +3 more
doaj  

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

open access: yesAdvanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang   +10 more
wiley   +1 more source

List of Licensees, 1952

open access: yes, 1952
A directory of licensed dentists and dental hygienists registered in Kansas. Dental hygienists were added to the directory starting with the 1935 List Issued by Kansas State Board of Dental Examiners, 1927-1943 Issued by Kansas State Dental Board, 1945 ...
Kansas. State Dental Board
core   +1 more source

Variation in ASUDAS Dental Morphological Traits Among Individuals with Different Early-Life Geographic Backgrounds: An Observational Pilot Study

open access: yesForensic Sciences
Background/Objectives: Nonmetric dental traits assessed using the Arizona State University Dental Anthropology System (ASUDAS) are valuable in forensic identification due to their population-specific variation.
Amisha Nayak   +6 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

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