Results 81 to 90 of about 732,409 (209)

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: January 16, 2016

, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on January 16, 2016.
CQ Transcriptions
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QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: February 14, 2016

, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on February 14, 2016.This meeting includes deliberation on recommendations for the Commission's final report to the President and ...
CQ Transcriptions
core  

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: December 3, 2015

, 2015
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on December 3, 2015. This meeting includes recommendations by the American Indian/Alaska Native subcommittee and the Disproportionality ...
CQ Transcriptions
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Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Association between dental neglect and alexithymia in individuals seeking dental care: A cross-sectional study

Journal of Oral Research and Review
Introduction: Alexithymia has become a paradigm linking emotion to health and is considered a stable personality trait. It may affect health by encouraging harmful behaviors, but more significantly, it is seen as a hindrance to effective patient ...
Banda Sri Deepti Sindhusha, Ravoori Srinivas, Srinivas Pachava   +2 more
doaj   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: January 28, 2016

, 2016
Transcript of a public teleconference held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) on January 28, 2016. This meeting includes deliberation on recommendations for the Commission's final report to the President and ...
CQ Transcriptions
core