Results 221 to 230 of about 842,825 (373)
Clinical implication of blood glucose monitoring in general dental offices: the Ehime Dental Diabetes Study. [PDF]
Harase T+18 more
europepmc +1 more source
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan+13 more
wiley +1 more source
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu+5 more
wiley +1 more source
East Williston Union Free School District and East Williston School District Clerical Unit No. 763000, CSEA Local 1000, AFSCME, AFL-CIO, Nassau County Educational Local 865 (2011) [PDF]
core +1 more source
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma+9 more
wiley +1 more source
A Medicaid Population’s Use of Physicians’ Offices for Dental Problems
Leonard A. Cohen+3 more
openalex +2 more sources
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu+9 more
wiley +1 more source